Attending to the rich entanglements of scientific and critical theory, contributors to this special issue of differences scrutinize phenomena in nature to explore new territory in feminist science studies. With a special focus on relating theory to method, these scholars generate new feminist approaches to scientific practice. Contributors probe this relationship by way of topics from the poetics of human-jellyfish interactions to a feminist reconsideration of a well-known thought experiment in thermodynamics. Two contributors analyze plant-insect encounter research to spin their own symbiotically inflected account of "affective ecologies." Technologies of human memory storage and retrieval lead one writer to interrogate how our understandings of memory and amnesia are currently under revision. Another contributor tracks the lively evolutionary and morphological theories that textile artisans manifest in material models of sea creatures. What emerges from these diverse essays is an approach to critical thinking that inhabits, elaborates, and feeds on scientific theory, holding feminist theory accountable to science and vice versa.